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Use eDrugSearch to check Doxepin price comparison results below. Women, especially, have a substantial risk of fatigue from statins, although more so from simvastatin. Upset stomach and diarrhea Both drugs can cause stomach upset and diarrhea. These side effects usually resolve over the course of a few weeks. Liver and kidney disease If you have kidney disease, atorvastatin could be a good choice for you because there is no need to adjust the dosage.
On the other hand, simvastatin can affect your kidneys when given at the highest dosage 80 mg per day. It may slow your kidneys.
Simvastatin also builds up in your system over time. This means that if you take it for an extended period of time, the amount of the drug in your system can really add up. Your doctor might have to adjust your dosage. However, based on results from a study by the American Heart Association , there is likely no increased risk of kidney injury between high-dose simvastatin and high-dose atorvastatin.
A few people who take statins develop liver disease. If you have darkened urine or pain in your side while taking either drug, call your doctor immediately. High blood sugar and diabetes Both simvastatin and atorvastatin can increase your blood sugar and your risk of developing diabetes. All statins may increase your hemoglobin A1C level, which is a measure of long-term blood sugar levels. Interactions Although grapefruit is not a drug, doctors recommend that you avoid consuming large amounts of grapefruit or grapefruit juice if you take statins.
The usage of all the excipients has been described. The release specification includes the check of all parameters relevant to this pharmaceutical form. Appropriate data concerning the control of the finished product support the compliance with the release specifications.
The packaging of the medicinal product complies with the current legal requirements. Stability studies under ICH conditions have been performed and data presented support the shelf life claimed in the SmPC, with a shelf life of 24 months when stored in the original package in order to protect from moisture.
The pharmaceutical quality of Atorvastatin 1A Pharma has been adequately shown. The results of tests carried out indicate satisfactory consistency and uniformity of important product quality characteristics.
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