Your doctor will normally advise you to stop taking Lisinopril before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Lisinopril. Lisinopril is not recommended in early pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Breast-feeding Tell your doctor if you are breast-feeding or about to start breast-feeding. Lisinopril is not recommended for mothers who are breastfeeding, and your doctor may choose another treatment for you if you wish to breast-feed, especially if your baby is newborn, or was born prematurely. Driving and using machines Lisinopril may cause dizziness or make you feel light headed especially if you are taking Lisinopril tablets for the first time.
If affected do not drive or operate machinery. Important information about some of the ingredients of Lisinopril Lisinopril contains mannitol which may have a mild laxative effect.
You should check with your doctor or pharmacist if you are not sure. The tablets should be swallowed preferably with a glass of water at approximately the same time each day. Lisinopril can be taken with or without food. The usual dose is: Adults and the elderly High blood pressure Treatment is generally started with one 10 mg tablet daily.
Some patients, such as those with kidney problems may require a lower starting dose. The dose will then be gradually increased every 2 4 weeks until your blood pressure is controlled. The usual long-term dosage is 20 mg once daily.
Special considerations Heart failure: If you have low blood sodium levels, your starting dose may be 2. Improving survival after a heart attack: If you have low blood pressure, your starting dose may be 2. Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Take as directed Lisinopril oral tablet is used for long-term treatment. This drug comes with serious risks if you don't take it as prescribed.
If you don't take it at all: This will raise your risk for a heart attack and stroke. If you stop taking it suddenly: There is limited information on the safety and ef fectiveness of Lisinopril in children.
Taking Lisinopril with other medicines Tell your doctor if you are taking or have recently taken any other medicines, including herbal remedies, health foods or supplements that you have bought yourself.
This also applies to medicines used some time ago. Some medicines may af fect the actions of other medicines. Talk to your doctor if you are taking any of the following medicines: Hyperkalaemia Elevations in serum potassium have been observed in some patients treated with ACE inhibitors, including lisinopril. Patients at risk for the development of hyperkalaemia include those with renal insufficiency, diabetes mellitus, or those using concomitant potassium-sparing diuretics, potassium supplements or potassium-containing salt substitutes, or those patients taking other drugs associated with increases in serum potassium e.
If concomitant use of the above-mentioned agents is deemed appropriate, regular monitoring of serum potassium is recommended see section 4. Diabetic patients In diabetic patients treated with oral antidiabetic agents or insulin, glycaemic control should be closely monitored during the first month of treatment with an ACE inhibitor see section 4.
Lithium The combination of lithium and lisinopril is generally not recommended see section 4. Pregnancy and lactation ACE inhibitors should not be initiated during pregnancy. Unless continued ACE inhibitor therapy is considered essential, patients planning pregnancy should be changed to alternative antihypertensive treatments which have an established safety profile for use in pregnancy.
When pregnancy is diagnosed, treatment with ACE inhibitors should be stopped immediately, and, if appropriate, alternative therapy should be started see sections 4. Use of lisinopril is not recommended during breast-feeding 4. When a diuretic is added to the therapy of a patient receiving lisinopril the antihypertensive effect is usually additive.
Patients already on diuretics and especially those in whom diuretic therapy was recently instituted, may occasionally experience an excessive reduction of blood pressure when lisinopril is added. The possibility of symptomatic hypotension with lisinopril can be minimised by discontinuing the diuretic prior to initiation of treatment with lisinopril see section 4.
Although in clinical trials, serum potassium usually remained within normal limits, hyperkalaemia did occur in some patients. Risk factors for the development of hyperkalaemia include renal insufficiency, diabetes mellitus, and concomitant use of potassium-sparing diuretics e. The use of potassium supplements, potassium-sparing diuretics or potassium-containing salt substitutes, particularly in patients with impaired renal function, may lead to a significant increase in serum potassium.
If lisinopril is given with a potassium-losing diuretic, diuretic -induced hypokalaemia may be ameliorated. Reversible increases in serum lithium concentrations and toxicity have been reported during concomitant administration of lithium with ACE inhibitors. Concomitant use of thiazide diuretics may increase the risk of lithium toxicity and enhance the already increased lithium toxicity with ACE inhibitors. Use of lisinopril with lithium is not recommended, but if the combination proves necessary, careful monitoring of serum lithium levels should be performed see section 4.
NSAIDs and ACE inhibitors exert an additive effect on the increase in serum potassium and may result in a deterioration of renal function. These effects are usually reversible. Rarely, acute renal failure may occur, especially in patients with compromised renal function such as the elderly or dehydrated.
Concomitant use of these agents may increase the hypotensive effects of lisinopril. Concomitant use with glyceryl trinitrate and other nitrates, or other vasodilators, may further reduce blood pressure. Clinical trial data has shown that dual blockade of the renin-angiotensin-aldosterone-system RAAS through the combined use of ACE-inhibitors, angiotensin II receptor blockers or aliskiren is associated with a higher frequency of adverse events such as hypotension, hyperkalaemia and decreased renal function including acute renal failure compared to the use of a single RAAS-acting agent see sections 4.
Concomitant use of certain anaesthetic medicinal products, tricyclic antidepressants, antipsychotics or muscle relaxants with ACE inhibitors may result in further reduction of blood pressure see section 4. Sympathomimetics may reduce the antihypertensive effects of ACE inhibitors. Epidemiological studies have suggested that concomitant administration of ACE inhibitors and antidiabetic medicinal products insulins, oral hypoglycaemic agents may cause an increased blood glucose lowering effect with risk of hypoglycaemia.
This phenomenon appeared to be more likely to occur during the first weeks of combined treatment and in patients with renal impairment. The use of ACE inhibitors is contraindicated during the second and third trimester of pregnancy see sections 4.
Clinical monitoring Before starting and during your treatment with 10mg drug, your doctor lisinopril check the following to tell if this drug is working or is 10mg for you: Take 10mg care with Lisinopril Tell your doctor if you have or have had any medical condition, especially the following: Hyperkalaemia Elevations in serum potassium have been observed in some patients treated with ACE inhibitors, including lisinopril, lisinopril 10mg tablet. This is more likely to occur in tablets with pre-existing renal impairment. If the following happens, stop taking the tablets and tell your doctor immediately or go to the casualty department at your nearest hospital: This lisinopril cause anxiety, sweating, and a fast heart rate. These lisinopril should be asked to report pregnancies to their tablets as soon lisinopril possible. Anaphylactoid Reactions During Membrane Exposure Sudden and potentially life-threatening anaphylactoid reactions have been reported in some patients dialyzed with high-flux membranes e. Please take this leaflet, lisinopril 10mg tablet, any remaining tablets 10mg the container with you to the hospital or doctor so that they know which tablets tablet consumed. If hypotension occurs and is considered to be due to this mechanism, lisinopril 10mg tablet, it can be corrected by volume expansion. Lisinopril Tablets should be used cautiously, if at all, lisinopril 10mg tablet, with these agents and tablet frequent monitoring of serum potassium.
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